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KMID : 0388420040140010065
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Konkuk Journal of Medical Sciences
2004 Volume.14 No. 1 p.65 ~ p.76
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Thrombocytopenia in pregnant women and neonate
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Lee Chang-Hoon
Kweon Hyuk-Jung
Kim Jeong-Eun
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Abstract
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It is important to distinguish from physiologic incidental thrombocytopenia (IP) in pregnant women and pathologic thrombocytopenic conditions associated with pregnancy involving pre-eclampsia/eclampsia, HELLP syndrome/AFLP, TTP/HUS, DIC, and infectious diseases. And also, they should be differentiated from ITP, SLE, and drug-induced thrombocytopenia which are immunologic disorders.
Although neonatal thrombocytopenia in most cases occurs from non-immune mediated dise-ases or pregnancy-induced thrombocytopenic conditions, but rarely, neonatal alloimmune thr-ombocytopenia (NAIT) which was caused by fetomaternal mismatch for human platelet all-oantigen (HPA) can occur.
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KEYWORD
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Thrombocytopenia, pregnant women, neonate, NAIT, HPA
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